Friendship is Healing

Meadowbrook falls into a mysterious new illness that is worse than anything else seen in Equestria. This illness, called MIDS, a magic form of AIDS, has never been seen since the Alicorn God Era because of high mastery of magic and is caused by mana being consumed by the HIV virus, making it adaptable as well as the illness. How it flared up again is not known yet, but the plague spreads like wildfire. Meadowbrook suggests going to find the formula for the ultimate cure of diseases, the Elixir of Life. But they find that all formulas written down have been destroyed, and eventually find a gem called the Philosopher's Stone, which contains the soul of Queen Elixia, the Alicorn goddess of health, healing, youth, mortality, medicine, remedy, and cures. But things immediately go to chaos when she reveals that the reason why the formula was destroyed is because of the Gods' amorality to mortals, as they didn't care if mortals contract illnesses and thus the Elixir of Life was outlawed and destroyed, thus breaking the trust between the Alicorn Gods and ponies. Betrayed by this amoral act, the ponies desecrate Alicornia to find other Philosopher's Stones and forcefully find the Elixir of Life. But this is actually a plot from another Alicorn god freed accidentally named King Epidemic, the Alicorn god of plague, illness, and pestilence, whom Elixia locked away into a gravely-ill magic tree until being freed slowly by emmets (large mythical ants), and reawaken the MIDS virus and sought to turn the ponies against their creators and gods as their final moments are spent trying and failing to stop the plague, as well as the one responsible for getting the Elixir of Life banned playing with the amorality of his kind so he could be free to do what he wanted. Thus with his plan working like a charm, the heroes must repair the damage done to the trust between the ponies and Alicorn Gods, stop the plague, and stop Epidemic for good.