Trista, Star, and their crew go to their next adventure on a world that takes place, in its time frame, in the years close to 2220. This is the world of Kipo and the Wonderbeasts, a world where mysterious mutagen genetics ended up on Earth and caused the world to be as it is now, with humans becoming a subterranean race and the surface being dominated by 'mutes', or mutant animals. They are told to find Kipo, a subterranean human with purplish skin trapped on the surface looking for her home with her friends Mandu, Wolf, Benson, and Dave. The Lodgers end up traveling there when the group doesn't respond to distress signals as they were captured by a monkey-human named Cass, who has tamed an entire family of mutes and has captured Trista's crew for their knowledge on the true origin of mutes, hoping that these secrets can be used to build her an army of mutes to defeat a powerful super-mute beyond anyone's comprehension of which all Mutes fear in religious-like fear: of which in Mute Culture is referred to as "The Great DN'Animal", but human society gave it the name of The Omni-Freak, a god-level super creature much worse than Scarlemagne who resides in the Africa of this Earth, or what was once Africa, now being renamed as "The Kingdom of DN'Animals", where a zealotical Mute Kingdom is where the Omni-Freak resides, protected by "The First DN'Animals", Gazziella and Cheetahtinusia, Mute/DN'Animals of a Gazelle and a Cheetah, self-proclaimed as "The First Daughters". With revelation that the Omni-Freak was created by a powerful race of Kaiju-Level Alien Mantids capable of Outer-God level manipulation of all things genetic and DNA, referred to as the "Biotiens", it is now a race to confront the Omni-Freak as he plans to create "A Genetic Storm" to turn all humans into "DN'Animal Purity" to finally "Quell all conflict" and "Complete (His) mission to the Biotiens" and that of his creator, a Biotien princess destined to inherit the throne cause of fully converting this earth away from "Human Genericness".